c3 and c4 complement levels in iron deficiency anemia

نویسندگان

mohammad reza keramati

mohammad hadi sadeghian

hossein ayatollahi

houshang rafatpanah

mohammad khajeh daluei

چکیده

background and objectives: complement proteins are some of the most important plasma proteins of the innate immune system. impaired immune function is reported in subjects who are iron deficient, and there are documents that these patients are prone to infection. this study was conducted to show whether serum c3 and c4 complement change in adult nonpregnant female with iron deficient anemia or not. methods: forty five normal subjects and 45 iron deficient anemia (hypochrom microcytic) cases were entered in this case and control study by using patients’ clinical history and also results of cbc, serum ferritin, iron and total iron binding capacity. serum c3, and c4 were measured in case and control subjects with nephlometry method, finally comparison between result of patients group and control group was done with using suitable statistical test. results: mean serum c3 and c4 in patient group was 1.28 ± 0.81 and 0.28 ± 0.23 g/l respectively and for control group was 1.39 ± 0.87 and 0.35 ± 0.25 g/l respectively. although serum complements were slightly lower in patient groups in compared to control group but this differences was not meaningful with t test. conclusion: this study showed serum c3 and c4 complements levels were not changed in iron deficiency anemia.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

C3 and C4 Complement Levels in Iron Deficiency Anemia

Background and Objectives: Complement proteins are some of the most important plasma proteins of the innate immune system. Impaired immune function is reported in subjects who are iron deficient, and there are documents that these patients are prone to infection. This study was conducted to show whether serum C3 and C4 complement change in adult nonpregnant female with iron deficient anemia or ...

متن کامل

Complement C3 and C4 and Metabolic Syndrome

The complement system is part of the innate immune system and plays a role in regulating inflammation. Increased inflammation is engaged in the development of adult cardiometabolic diseases such as insulin resistance, dyslipidemia, atherosclerosis, and hypertension. Adipose tissue not only produces complement but is also a potential target for complement activity. Obese adults and adults with c...

متن کامل

Anemia, Iron Deficiency, and Iron Deficiency Anemia

Anemia is one of the most widespread public health problems, especially in developing countries, and has important health and welfare, social, and economic consequences. These include impaired cognitive development, reduced physical work capacity, and in severe cases increased risk of mortality, particularly during the perinatal period. There is also evidence that anemia may result in reduced g...

متن کامل

Iron Deficiency and Iron Deficiency Anemia in Children with Febrile Seizure

Abstract Background Febrile seizure (FS) is the most common childhood seizures which occur in 2-5% of children. Studies about association between iron deficiency and febrile seizure have shown contradictory results. The purpose of this study was to compare the iron status of children with first febrile seizure and healthy control group. Materials and Methods In an analytic case-control ...

متن کامل

Iron deficiency anemia and seizure in a kitten

The aim of this article was to describe the clinical management of a case with seizure, possibly due toiron deficiency anaemia (IDA) in a kitten. A 38-day-old female European shorthair cat was presented withacute onset of impaired consciousness, seizures and lateralised upper motor neuron tetraparesis. Haematology results showed severe microcytic hypochromic anaemia with marked anisocytosis and...

متن کامل

Genome-Wide Association Study for Serum Complement C3 and C4 Levels in Healthy Chinese Subjects

Complement C3 and C4 play key roles in the main physiological activities of complement system, and their deficiencies or over-expression are associated with many clinical infectious or immunity diseases. A two-stage genome-wide association study (GWAS) was performed for serum levels of C3 and C4. The first stage was conducted in 1,999 healthy Chinese men, and the second stage was performed in a...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pathology

ناشر: iranian society of pathology

ISSN 1735-5303

دوره 6

شماره 2 2011

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023